Emgality is a monoclonal antibody that blocks CGRP, a protein that plays a role in migraine and cluster headaches.
It comes in a prefilled pen or syringe that you inject under your skin once a month. Your doctor will help you choose the right site for your injections.
The calcitonin gene-related peptide (CGRP) causes blood vessels in the brain to widen, causing migraine pain. Emgality stops CGRP from binding to the CGRP receptor and prevents blood vessels from widening, which can help reduce migraine symptoms.
Emgality is available as a prefilled pen or syringe and is injected under the skin. It is used to prevent migraine headaches or treat episodic cluster headaches.
Migraine and cluster headaches are caused by a chemical called calcitonin gene-related phosphoprotein (CGRP). It causes blood vessels in the brain to widen, leading to migraine symptoms such as pain, nausea, vomiting and dizziness.
Emgality is a monoclonal antibody that binds to the CGRP ligand and prevents it from binding to the CGRP receptor. It also helps stop blood vessels from widening and helps them return to their normal size.
Emgality benefits reduce nausea, which is one of the most common side effects associated with migraine headaches. Nausea can affect the way you feel, including your ability to move and work.
The medicine works by blocking the activity of a substance called calcitonin gene-related peptide (CGRP). Increased levels of CGRP have been linked to migraine headaches.
CGRP is involved in inflammation and vasodilation (widening of blood vessels). By blocking the activity of CGRP, Emgality helps to relieve some of the symptoms of migraine.
Emgality is a monoclonal antibody that blocks the activity of CGRP in your body. It is used to prevent migraine headaches and to treat cluster headache episodes.
One study found that people with chronic migraine who were treated with emgality had 102.6 fewer severity-weighted hours of pain per month on average than those who took placebo. This amount of relief is more than double what is seen with other anti-migraine medications.
Migraine is a common medical condition that can cause pulsating headache pain and other symptoms like nausea, vomiting, and sensitivity to light or sound. It is usually more severe in women than men, and it can affect their everyday life.
It is also a serious condition that can be life-threatening. Taking Emgality may reduce your chances of having a serious allergic reaction (such as swelling of the face, lips, or throat).
Your doctor will decide how long to use this medicine and when you need to inject it. It is important to take it at the same time each month. If you miss a dose, inject it as soon as possible and then resume monthly dosing.
In clinical studies of Emgality, fatigue (lack of energy) was not reported as a side effect. However, fatigue can be a common symptom of migraine that people may experience before, during, or after a headache.
If you have fatigue, talk with your doctor about ways to improve your energy levels during your treatment with Emgality. Your doctor may recommend a different medication for your migraine treatment if you have this problem.
Taking Emgality with other medicines that contain acetaminophen can increase your risk for liver problems. Ask your doctor about the right dose of acetaminophen and other medications to take with Emgality.
Emgality comes in a prefilled pen or syringe and is given as an injection under the skin each month to prevent migraine headaches. It also is used to treat episodic cluster headaches. For this treatment, the medicine is given once and then repeated monthly only if needed to stop cluster headaches.